PUBLICATIONs du labex
1. Immunité & Cancer
Grinberg-Bleyer Y, et al. J Immunol. 2018 Apr 1;200(7):2362-2371
Voisin A., Grinberg-Bleyer Y. International Review of Cell and Molecular Biology. 2020, doi.org/10.1016/bs.ircmb.2020.10.006
Lalle G, Twardowski J, Grinberg-Bleyer Y. Cells. 2021 Feb 9;10(2):355
Ronin E, et al, PNAS, 2021, Vol. 118 No. 13
Lalle G, et al, Grinberg-Bleyer Y. Scientific Reports, 2021, 11:19674
Akagbosu B et al, Nature 2022
Lainé A et al, Nature com, 2021
Bouchet M, et al, Cancer Research 2020
Ferreira C, Nature Immunology 2020
Worthington J.J, et al, Immunity 2015
Havenar-Daughton C, Blood 2012
Bonaventura P et al, Sci Adv. 2022 Jan 28;8(4):eabj3671.
Hubert M et al, Sci Immunol. 2020 Apr 17;5(46):eaav3942.
Ramos RN et al, Clinical & Translational Immunology, 9(2):e1108, 2020.
Shekarian T et al, Sci Transl Med. 2019 Oct 23;11(515):eaat5025.
Gourdin N et al, Cancer Res. 2018, Jul 1;78(13):3604-3618.
BREVETS ACCEPTES (plusieurs en cours non mentionnés)
WO 2012/131004 « Anti-ICOS antibody and there use thereof » Inventors: C. CAUX, J. FAGET, C. MENETRIER-CAUX, D. OLIVE
WO 2014/033327 « antibodies directed against ICOS for treating graft versus host disease” Inventors: G. MARODON, C. MÉNÉTRIER-CAUX, J. NUNES, D. OLIVE, B. SALOMON
EP22243 use of anti ITGb8 antibodies in cancer therapy
2. Virus et Cancer
Locatelli M, et al, 2022;14(3):527-551
Martinez MG et al,. mBio. 2022 Apr 26;13(2):e0288821
Barnault R et al, 2022 Nov;76(5):1345-1359
Gallard C et al,. J Hepatol. 2022 Jul;77(1):29-41
BREVET
Barnault R, Verzeroli C, Fournier C, Gibert B, Mehlen P, Zoulim F, Parent R. Anti-netrin-1 antibody to treat liver inflammation. 2022. #BET22L0611. Cabinet Lavoix, Lyon
3. Mort Cellulaire et Cancer
P. Mehlen, C. Delloye-Bourgeois, A. Chédotal, Nat Rev Cancer. 11, 188–197 (2011).
M. Castets et al., Nature. 482, 534–537 (2012).
L. Broutier et al., EMBO Mol Med. 8, 96–104 (2016).
H. Wang et al., Molecular Cell. 72, 413-425.e5(2018).
M. Grandin et al., Cancer Cell. 29, 173–185 (2016).
C. Dominici et al., Nature. 545, 350–354 (2017).
O. Meurette et P. Mehlen Cancer Cell, 34, 536-548 (2018).
PJ. Sung et al. Cancer Res. pii: canres.2952.2018 (2019).
PA. Bissey et al, Cancer Res. 80(10):1970-1980 (2020).
A. Boussouar et al, Cancer Res. pii: canres.1590.2018. (2020).
M. Jasmin et al, EMBO J.;40(3):e105537 (2021).
S. Jiang et al, EMBO Mol Med. 2021 Apr 9;13(4):e12878 (2021).
P. Mehlen and L.Fattet, Nat Mater. 20(6):722-723 (2021).
Y Sun et al, Proc Natl Acad Sci U S A. 118: e2103319118 (2021).
Savary C., et al. https://bit.ly/SavaryetalbioRxiv, soumis
Huchedé P, Leblond P, Castets M. Biomedicines. 2022 Jun 3;10(6):1311
Savary C, Picard C, Corradini N, Castets M. Int J Mol Sci. 2022 Jun 4;23(11):6310
Coursier D, Coulette D, Leman H, Grenier E, Ichim G. Live-cell imaging and mathematical analysis of the "community effect" in apoptosis. Apoptosis. 2023 Apr;28(3-4):326-334
Martin N, Popgeorgiev N, Ichim G, Bernard D. BCL-2 proteins in senescence: beyond a simple target for senolysis? Nat Rev Mol Cell Biol. 2023 Aug;24(8):517-518.
Popgeorgiev N, Gil C, Berthenet K, Bertolin G, Ichim G. Shedding light on mitochondrial outer-membrane permeabilization and membrane potential: State of the art methods and biosensors. Semin Cell Dev Biol. 2023 Jul 10:S1084-9521(23)00141-6.
Piecyk M, Triki M, Laval PA, Duret C, Fauvre J, Cussonneau L, Machon C, Guitton J, Rama N, Gibert B, Ichim G, Catez F, Bourdelais F, Durand S, Diaz JJ, Coste I, Renno T, Manié SN, Aznar N, Ansieau S, Ferraro-Peyret C, Chaveroux C. The stress sensor GCN2 differentially controls ribosome biogenesis in colon cancer according to the nutritional context. Mol Oncol. 2023 Jul 15.
Julien Nadjar, Sylvain Monnier, Estelle Bastien, Anne-Laure Huber, Christiane Oddou, Léa Bardoulet, Gabriel Ichim, Christophe Vanbelle, Bénédicte Py, Olivier Destaing, Virginie Petrilli.
An optogenetic approach to control and monitor inflammasome activation; bioRxiv 2023.07.25.550490.
Catherine Jamard, Clara Gil, Marie Castets, Gabriel Ichim, Kathrin Weber. Lysosomal MLKL is balanced by ESCRT to control cell death. bioRxiv 2023.08.29.555049.
Albaret MA, Aïmontché E, Bendriss-Vermare N, Diaz JJ, Gil C, Hedjam J, Ichim G, Morin C, Mourksi NE, Nguyen TTM, Picant V, Picard E, Popgeorgiev N, Tirode F, Vanacker H, Puisieux A, Mehlen P. Actualités en recherche en oncologie : l’essentiel du cinquième Symposium International 2022 du Centre de recherche en cancérologie de Lyon [Oncology research congress: The essentials of the fifth International Symposium 2022 of the Cancer Research Center of Lyon]. Bull Cancer. 2023 Oct 6:S0007-4551(23)00339-9. French. doi: 10.1016/j.bulcan.2023.07.003.
BREVET
EP21305446.3 - Dérivation d’organoïdes de rhabdomyosarcomes – Laura Broutier.
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4. Cellules Souches et Cancer
Aksoy, I., … Savatier, P. (2014). Nat. Commun. 5:3719-33.
Chen H, … Savatier P. (2015) Nat. Comm. 6:7095-112.
Osteil, P, … Savatier, P. (2016Stem Cell Rep. 7:383-98.
Aksoy, I… Savatier. P. (2021). Stem Cell Rep 16:56-74.
Bouchereau, W et al, (2022). Development 149 dev200538.
Betizeau et al, (2013) Neuron 80:442-457.
Dehay C, et al, (2015) Neuron 85:683-694.
Cortay V, et al, (2020) Front Cell Dev Biol, 16;8:588814.
Dehay C, Kennedy H (2020) Evolution of the human brain. Science, 369(6503):506-507.
Florence Wianny et al (2022). Adv Sci (Weinh):e2103827.
BREVET
Wianny F, Baquerre C, Waltispurger J, Dehay C, Pain B (2020) Production of cortical organoids as a model for corticogenesis of primates: an assay for assessment of pathologies and drug screening. DI-RV InsermTransfert.
5. Epigénétique et Cancer
Marcel V, et al, NAR Cancer, Volume 2, Issue 4, December 2020, zcaa036
Therizols G et al, Nat Commun 13, issue 1, 173 (2022)
Morin C et al, Biochim Biophys Acta Rev Cancer. 2022 May;1877(3):188718.
Nguyen Van Long F et al, BMC Cancer. 2022 May 11;22(1):526.
Mourksi NE et al, Mol Oncol. 2022 Nov 12.
BREVET
Marcel V, Diaz JJ, Catez F, Kielbassa J. RiboPRINT – Ribosomal RNAs 2’O-methylation as a novel source of biomarkers relevant for diagnosis, prognosis and therapy of cancers. 20306461.3 (27/11/2020). PCT/EP2021/083429. Date de dépôt : 29 novembre 2021 - Priorité : EP N°20306461.3 du 27/11/2020
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6. Plasticité et Cancer
Pommier et al, Nature Communications,11(1):3431, 2020.
Puisieux A, et al, Cancer Cell, 33: 164-172, 2018.
Morel AP et al, Nature Medicine, 23: 568-578, 2017.
Puisieux A et al, Nature Cell Biology, 16: 488-494, 2014.
Caramel J et al, Cancer Cell, 24(4):466-80, 2013.
7. Stratégies thérapeutiques du Cancer
Chettab K, et al, (2022) Mol Pharm. Mar 7;19(3):929-935.
Chettab K, et al, (2017) Mol Pharm. Feb 6;14(2):441-447.
Lafond M et al, (2016) Ultrasound Med Biol. Jan;42(1):220-31.
Chettab K, et al, (2015) PLoS One. Aug 14;10(8):e0134247.
Wischhusen J, et al, (2018) Theranostics. Oct 6;8(18):5126-5142.
Fant C, et al, (2021) Ultrasound Med Biol. Oct;47(10):2941-2957.
Vion-Bailly J et al, (2019) Sci Rep. Sep 24;9(1):13738.